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Measuring oxidative stress

Oxidative stress affects may exert strong effects on individual health and fitness. Lipid peroxidation products are widely used as markers of oxidative damage in the organism. This paper investigates the relationship between circulating lipids and two common markers of oxidative damage (plasma levels of malondialdehyde –MDA- and hydroperoxides- d-ROMs assay kit-). The study was performed on several bird species belonging to different taxonomic groups and with different diets. In all cases, plasma triglyceride levels positively and significantly correlated with lipid peroxidation markers, explaining between 8% and 34% of their variability. These results indicate that lipid peroxidation markers levels must be statistically controlled for the lipid concentration in the sample in order to avoid undesirable biases and wrong interpretations. informacion[at]ebd.csic.es Pérez-Rodríguez et al (2015) Measuring oxidative stress: the confounding effect of lipid concentration in measures of lipid peroxidation Physiol. Biochem. Zool 88 3 345-351 DOI: 10.1086/680688


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