Salinity of freshwater systems is increasing due to habitat modification, road salt run-off, industrial/mining wastes, and sea level rise. Because amphibians are adapted for life in freshwater systems, even small increases in salinity can be physiologically stressful, causing disruption of homeostasis with direct and indirect negative health consequences. In this seminar, I will discuss my research examining the health effects of anthropogenic increases in salinity across life history stages on wood frogs, Lithobates sylvaticus, in two different contexts: road salt run-off and habitat disturbance.