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Cross-species transcriptomics uncovers genes underlying genetic accommodation of developmental plasticity in spadefoot toads

A new research from the Doñana Biological Station has compared the transcriptome-wide responses of two species of spadefoot toads with differing capacity for developmental acceleration of their larvae in the face of a shared environmental risk: pond drying. By comparing gene expression profiles over time and performing cross-species network analyses, the research team identified orthologues and functional gene pathways whose environmental sensitivity in expression have diverged between species.